MBD3 antibody (Methyl-CpG Binding Domain Protein 3) (C-Term)

Details for Product anti-MBD3 Antibody No. ABIN4889329, Supplier: Log in to see
Antigen
  • xmbd3
  • MGC69548
  • MBD3
  • DKFZp459N1635
  • AI181826
  • AU019209
  • methyl-CpG binding domain protein 3 S homeolog
  • methyl-CpG binding domain protein 3
  • mbd3.S
  • mbd3
  • MBD3
  • Mbd3
Alternatives
anti-Human MBD3 antibody for Western Blotting
Epitope
C-Term
17
14
14
7
6
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Hamster, Human, Monkey, Mouse (Murine), Rat (Rattus)
117
32
12
6
4
4
4
4
3
3
3
3
1
1
1
1
Host
Rabbit
78
37
2
Clonality
Polyclonal
Conjugate
This MBD3 antibody is un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
105
45
28
18
9
8
4
2
1
1
Options
Supplier
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Immunogen Synthetic peptide of derived from C terminal part of human MBD3.
Specificity Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)
Purification Purified (protein A)
Plasmids, Primers & others Plasmids, Primers & others MBD3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MBD3 (MBD3 Antibody Abstract)
Background Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
Gene ID 53615
UniProt O95983
Pathways Chromatin Binding
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1M, glycine 0,1M
Storage 4 °C/-20 °C
Storage Comment Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 6 months
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