MAP1LC3A antibody (Internal Region)

Catalog No. ABIN4889349

The Rabbit Polyclonal anti-MAP1LC3A antibody (ABIN4889349) specifically detects MAP1LC3A in WB, ELISA and IHC (fro). The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for MAP1LC3A antibody (Internal Region) (ABIN4889349)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAP1LC3A Antibody

Binding Specificity: Internal Region

Specificity: Reacts with human MAP1LC3A

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reacts with mouse and rat proteins due to 100 % of sequence homology. May crossreact with other species due to sequence homology.

Purification: Purified (protein A)

Immunogen: Synthetic peptide derived from internal part of human MAP1LC3A

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC-F 1:200 - 1:2 000 WB1:500 - 1:5 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A)

Background: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Gene ID: 84557

UniProt: Q9H492

Pathways: Autophagy