Caspase 8 antibody

Catalog No. ABIN4901141

The Mouse Monoclonal anti-Caspase 8 antibody has been validated for WB, ELISA, FACS and IHC (p). It is suitable to detect Caspase 8 in samples from Human, Mouse, Rat and Monkey.

Quick Overview for Caspase 8 antibody (ABIN4901141)

Target: Caspase 8 (CASP8)

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1H11

Product Details anti-Caspase 8 Antibody

Purpose: Mouse monoclonal to Caspase-8.

Specificity: Caspase-8 Monoclonal Antibody detects endogenous levels of Caspase-8 protein.

Characteristics: Mouse Monoclonal to Caspase-8.

Purification: Affinity purification

Immunogen: Purified recombinant fragment of human Caspase-8 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000

Comment:

Isoform 1, isoform 5 and isoform 7 are expressed in a wide variety of tissues. Highest expression in peripheral blood leukocytes, spleen, thymus and liver. Barely detectable in brain, testis and skeletal muscle.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: Caspase-8

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades