Collagen Type I antibody

Catalog No. ABIN4901289

This anti-Collagen Type I antibody is a Mouse Monoclonal antibody detecting Collagen Type I in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Collagen Type I antibody (ABIN4901289)

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Collagen Type I antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Collagen Type I Antibody

Purpose: Collagen I is a protein encoded by the COL1A1 gene which is approximately 138,9 kDa. Collagen I is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling, focal adhesion and the phospholipase-C pathway. It is a pro-alpha-1 chain of type I collagen whose triple helix comprises two alpha-1 chains and one alpha-2 chain. Collagen I is expressed in the bone, skin, eye, lung and nervous system. Mutations in the COL1A1 gene may result in Caffey disease and Ehlers-Danlos syndrome. STJ98915 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen I protein.

Specificity: The antibody detects endogenous Collagen I protein.

Characteristics: Mouse Monoclonal to Collagen I.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: synthetic peptide derived from Collagen I.

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Alternative Name: Collagen I

Molecular Weight: 139kDa

Gene ID: 1277

UniProt: P02452