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Collagen Type I antibody

COL1 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Mouse Monoclonal 3G3 unconjugated
Catalog No. ABIN782308
  • Target See all Collagen Type I (COL1) Antibodies
    Collagen Type I (COL1) (Collagen, Type I (COL1))
    Reactivity
    • 95
    • 62
    • 60
    • 20
    • 18
    • 17
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 69
    • 34
    • 14
    Mouse
    Clonality
    • 83
    • 34
    Monoclonal
    Conjugate
    • 58
    • 14
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    This Collagen Type I antibody is un-conjugated
    Application
    • 70
    • 47
    • 38
    • 36
    • 32
    • 28
    • 27
    • 25
    • 19
    • 18
    • 17
    • 9
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    Recognizes Collagen type I (COL1A1).
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    Purification
    Protein A Chromatography
    Immunogen
    Recombinant Human COL1A1
    Clone
    3G3
    Isotype
    IgG3
    Top Product
    Discover our top product COL1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Collagen Type I (COL1) (Collagen, Type I (COL1))
    Alternative Name
    Collagen Type I (COL1 Products)
    Synonyms
    collagen type III alpha 1 chain antibody, COL3A1 antibody
    Background
    Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2
    Gene ID
    1277
    NCBI Accession
    NP_000079
    UniProt
    P02452
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