Integrin beta 2 antibody (FITC)

Catalog No. ABIN490150

This Rat Monoclonal antibody specifically detects Integrin beta 2 in FACS, WB, IHC, IP, IHC (fro), Func, BR and Neut. It exhibits reactivity toward Mouse.

Quick Overview for Integrin beta 2 antibody (FITC) (ABIN490150)

Target: Integrin beta 2 (ITGB2)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Clone: M18-2

Product Details anti-Integrin beta 2 Antibody (FITC)

Specificity: The rat monoclonal antibody M18/2 recognizes CD18 antigen (integrin beta2 subunit, beta2 integrin), a 95 kD type I transmembrane protein expressed on all leukocytes.

Purification: Protein G purified

Immunogen: Murine cytotoxic T cell glycoproteins.

Isotype: IgG2a

Application Details

Application Notes: Approved: Block, Flo, Func, IHC, IHC-Fr, IP, Neut, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. The reagent is designed for Flow Cytometry analysis. Suggested working concentration is 3 μg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2 / MAC-1 / CD18

Background: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation