FYN antibody

Catalog No. ABIN4901570

The Mouse Monoclonal anti-FYN antibody is suitable to detect FYN in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and ELISA.

Quick Overview for FYN antibody (ABIN4901570)

Target: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This FYN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4B8-E7-A8

Product Details anti-FYN Antibody

Purpose: Mouse monoclonal to Fyn.

Specificity: This antibody detects endogenous levels of Fyn and does not cross-react with related proteins.

Characteristics: Mouse Monoclonal to Fyn.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Purified recombinant human Fyn protein fragments expressed in E.coli.

Isotype: IgG2b

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Comment:

Isoform 1 is highly expressed in the brain. Isoform 2 is expressed in cells of hemopoietic lineages, especially T-lymphocytes.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for FYN

Target: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Alternative Name: Fyn

Molecular Weight: 59kDa

Gene ID: 2534

UniProt: P06241

Pathways: JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling