Iodotyrosine Deiodinase (IYD) antibody

Details for Product No. ABIN4904099
Antigen
  • MGC85450
  • C6orf71
  • DEHAL1
  • TDH4
  • dJ422F24.1
  • 0610009A07Rik
  • AI265638
  • Dehal1
  • RGD1309288
  • IYD-1
  • iodotyrosine deiodinase
  • iodotyrosine deiodinase L homeolog
  • IYD
  • iyd.L
  • iyd
  • Iyd
Reactivity
Mouse (Murine)
13
3
3
1
1
1
Host
Rabbit
13
1
Clonality
Polyclonal
Application
Western Blotting (WB)
14
9
4
Options
Immunogen Recombinant protein of human IYD.
Isotype IgG
Characteristics This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Purification Affinity purification
Antigen
Alternative Name IYD (IYD Antibody Abstract)
Gene ID 389434
UniProt Q6PHW0
Pathways Thyroid Hormone Synthesis
Application Notes WB 1:200-1:2000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C.
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