SQLE antibody

Catalog No. ABIN4905291

Product Details anti-SQLE Antibody

Target: SQLE (Squalene Epoxidase (SQLE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SQLE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.

Purification: Affinity purification

Immunogen: Recombinant protein of human SQLE.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 , IHC 1:20-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for SQLE

Target: SQLE (Squalene Epoxidase (SQLE))

Alternative Name: SQLE (SQLE Products)

Synonyms: An03g03770 antibody, AO090701000685 antibody, AI323792 antibody, squalene epoxidase antibody, SQLE antibody, ANI_1_450034 antibody, AOR_1_1218114 antibody, CC1G_03987 antibody, BDBG_08449 antibody, MCYG_02365 antibody, TERG_05717 antibody, Sqle antibody

Gene ID: 6713

UniProt: Q14534