ERK2 antibody (N-Term)

Catalog No. ABIN492383

Product Details anti-ERK2 Antibody

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Binding Specificity: AA 1-360, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes human MAPK1. Other species not tested.

Characteristics: Synonyms: Mitogen-activated protein kinase 1, p42-MAPK, ERT1, PRKM1, PRKM2, MAP kinase 2,MAPK2, MAPK1, Extracellular signal-regulated kinase 2

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human MAPK1 (1-360aa) purified from E. coli

Clone: AT1A4

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 500 - 1: 3,000). Immunofluorescence (1: 500 - 1: 3,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Alternative Name: ERK2 (MAPK1 Products)

Synonyms: ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody

Background: Mitogen-activated protein kinases (MAPKs) are reported to be critical regulatory factors for the growth andmigration of various cell types including vascular smooth muscle cells (VSMCs). It has also been reported that the activation of the MAP kinase family, extracellular signal regulated kinases 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) via Src activation is important for AII-induced migration of VSMCs. MAPKs are intracellular signal-transduction pathways that have been shown to play a central role in the development of injury following ischemia in the brain and heart. MAPKs regulate gene expression, which is important in cell injury/repair and proliferation/differentiation.Synonyms: ERT1, Extracellular signal-regulated kinase 2, MAP kinase 2, MAPK1, MAPK2, Mitogen-activated protein kinase 1, PRKM1, PRKM2, p42-MAPK

Gene ID: 5594

UniProt: P28482

Pathways: MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins