Recombinant Glypican 3 antibody (full length)

Catalog No. ABIN4949347

The Rabbit Monoclonal anti-Glypican 3 antibody is suitable to detect Glypican 3 in samples from Human and Rat. It has been validated for FACS, IF and IHC (p).

Quick Overview for Recombinant Glypican 3 antibody (full length) (ABIN4949347)

Target: Glypican 3 (GPC3)

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Glypican 3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GPC3-1534R

Product Details anti-Glypican 3 Antibody

Binding Specificity: full length

Purpose: Recombinant Glypican-3 Antibody / Rabbit Monoclonal

Purification: Protein A affinity chromatography

Immunogen: A full length human protein was used as the immunogen for the recombinant Glypican-3 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Glypican-3 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Glypican-3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Glypican 3

Target: Glypican 3 (GPC3)

Alternative Name: Glypican-3

Background: Glypican-3 is a proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. [UniProt]

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process