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Calnexin antibody

CANX Reactivity: Human WB, ELISA, IHC (p), IF/ICC Host: Mouse Monoclonal CANX-1541 unconjugated
Catalog No. ABIN4949485
  • Target See all Calnexin (CANX) Antibodies
    Calnexin (CANX)
    Reactivity
    • 116
    • 73
    • 72
    • 48
    • 34
    • 31
    • 31
    • 29
    • 29
    • 26
    • 25
    • 25
    • 22
    • 21
    • 20
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 117
    • 22
    • 7
    Mouse
    Clonality
    • 114
    • 33
    Monoclonal
    Conjugate
    • 70
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Calnexin antibody is un-conjugated
    Application
    • 122
    • 79
    • 57
    • 56
    • 39
    • 28
    • 26
    • 25
    • 20
    • 14
    • 13
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC)
    No Cross-Reactivity
    Rat (Rattus)
    Purification
    Protein G affinity chromatography
    Immunogen
    A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
    Clone
    CANX-1541
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CANX Primary Antibody
  • Application Notes
    Titering of the Calnexin antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL (order BSA-free format for coating),WB: 1-2 μg/mL,IF/ICC: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the Calnexin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    Calnexin (CANX)
    Alternative Name
    Calnexin (CANX Products)
    Synonyms
    CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
    Background
    It recognizes a protein of 90  kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
    Pathways
    MAPK Signaling, Thyroid Hormone Synthesis
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