CFTR / Cystic Fibrosis Transmembrane Regulator antibody

Catalog No. ABIN4949559

This Mouse Monoclonal antibody specifically detects CFTR / Cystic Fibrosis Transmembrane Regulator in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CFTR / Cystic Fibrosis Transmembrane Regulator antibody (ABIN4949559)

Target: CFTR / Cystic Fibrosis Transmembrane Regulator

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM176

Product Details

Purpose: CFTR Antibody

Purification: Protein G affinity chromatography

Immunogen: Human partial recombinant protein was used as the immunogen for this CFTR antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CFTR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: CFTR / Cystic Fibrosis Transmembrane Regulator

Background: Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]

UniProt: P13569