Transferrin Receptor antibody (Extracellular)

Catalog No. ABIN4949928

This Mouse Monoclonal antibody specifically detects Transferrin Receptor in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Transferrin Receptor antibody (Extracellular) (ABIN4949928)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: TFRC-1817

Product Details anti-Transferrin Receptor Antibody

Binding Specificity: AA 94-212, Extracellular

Purpose: CD71 Antibody / Transferrin Receptor (Extracellular domain) (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CD71 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD71 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71

Background: It recognizes a ~85-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis