CGRP antibody

Catalog No. ABIN4950541

Product Details anti-CGRP Antibody

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CGRP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF were used as the immunogen for the CGRP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CGRP antibody should be determined by the researcher.

1. Required HIER for FFPE samples: Boil the paraffin sections in pH 6, 10 mM citrate buffer for 20 minutes and allow to cool prior to testing.\. IHC (FFPE): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CGRP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CGRP

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Alternative Name: CGRP / CALCA (CALCA Products)

Synonyms: CALC1 antibody, CGRP antibody, CGRP-I antibody, CGRP1 antibody, CT antibody, KC antibody, CALC antibody, CALCA antibody, CALC3 antibody, ci-ct antibody, calca antibody, CA antibody, CGRP-1 antibody, Calc antibody, Calc1 antibody, Cgrp antibody, Ct antibody, Ctn antibody, calcitonin antibody, CAL6 antibody, Cal1 antibody, RATCAL6 antibody, CGRPI antibody, calc antibody, cgrp antibody, zgc:92886 antibody, calcitonin related polypeptide alpha antibody, calcitonin related polypeptide beta antibody, calcitonin-related polypeptide alpha antibody, calcitonin antibody, calcitonin/calcitonin-related polypeptide, alpha antibody, calcitonin-related polypeptide beta antibody, calcitonin gene-related peptide 2 antibody, CALCA antibody, CALCB antibody, ci-ct antibody, calca antibody, Calca antibody, LOC100008771 antibody

Background: Calcitonin gene-related peptide 1, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q99JA0

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour