ILK antibody

Catalog No. ABIN4951471

Product Details anti-ILK Antibody

Target: ILK (Integrin-Linked Kinase (ILK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ILK antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids M1-H203 from the human protein were used as the immunogen for the Integrin linked kinase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Integrin linked kinase antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Integrin linked kinase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Alternative Name: Integrin linked kinase (ILK) (ILK Products)

Synonyms: CG10504 antibody, CT29478 antibody, DmILK antibody, Dmel\\CG10504 antibody, ILK antibody, ilk antibody, l(3)78Ca antibody, p59 antibody, AA511515 antibody, ESTM24 antibody, zgc:65842 antibody, ILK-1 antibody, ILK-2 antibody, P59 antibody, p59ILK antibody, Integrin linked kinase antibody, integrin linked kinase antibody, integrin linked kinase S homeolog antibody, integrin-linked protein kinase antibody, integrin-linked kinase antibody, Ilk antibody, ILK antibody, ilk.S antibody, CpipJ_CPIJ016644 antibody, Bm1_20815 antibody, Tsp_07213 antibody, Tsp_07224 antibody, Tsp_15354 antibody, ilk antibody

Background: ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration