PINK1 antibody (AA 118-147)

Catalog No. ABIN3032405

The Rabbit Polyclonal anti-PINK1 antibody is suitable to detect PINK1 in samples from Human and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for PINK1 antibody (AA 118-147) (ABIN3032405)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PINK1 Antibody

Binding Specificity: AA 118-147

Purpose: PINK1 Antibody

Purification: Purified

Immunogen: A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1

Background: Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.

UniProt: Q9BXM7

Pathways: Autophagy