PCSK9 antibody (AA 479-508)

Catalog No. ABIN3032342

The Rabbit Polyclonal anti-PCSK9 antibody is suitable to detect PCSK9 in samples from Human. It has been validated for WB, IHC, ELISA and FACS.

Quick Overview for PCSK9 antibody (AA 479-508) (ABIN3032342)

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-PCSK9 Antibody

Binding Specificity: AA 479-508

Purification: Purified

Immunogen: A portion of amino acids 479-508 from the human protein was used as the immunogen for this anti-PCSK9 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the anti-PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the anti-PCSK9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Alternative Name: PCSK9

Background: PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

UniProt: Q8NBP7