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Bcl-2 antibody (AA 49-76)

The Rabbit Polyclonal anti-Bcl-2 antibody (ABIN3030096) specifically detects Bcl-2 in WB and ELISA. The antibody is reactive with Human samples.
Catalog No. ABIN3030096
$612.54
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Quick Overview for Bcl-2 antibody (AA 49-76) (ABIN3030096)

Target

See all Bcl-2 (BCL2) Antibodies
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity

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  • 1
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Human

Host

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  • 4
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Rabbit

Clonality

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Polyclonal

Conjugate

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This Bcl-2 antibody is un-conjugated

Application

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Western Blotting (WB), ELISA
  • Binding Specificity

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    AA 49-76

    Purification

    Antigen affinity purified

    Immunogen

    A portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the anti-Bcl-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    Alternative Name

    Bcl-2

    Background

    Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

    UniProt

    P10415

    Pathways

    MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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