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BAX antibody (AA 47-78)

This anti-BAX antibody is a Rabbit Polyclonal antibody detecting BAX in WB and ELISA. Suitable for Human.
Catalog No. ABIN3030141

Quick Overview for BAX antibody (AA 47-78) (ABIN3030141)

Target

See all BAX Antibodies
BAX (BCL2-Associated X Protein (BAX))

Reactivity

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  • 153
  • 136
  • 46
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Human

Host

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Rabbit

Clonality

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  • 90
Polyclonal

Conjugate

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This BAX antibody is un-conjugated

Application

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Western Blotting (WB), ELISA
  • Binding Specificity

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    AA 47-78

    Purification

    Antigen affinity purified

    Immunogen

    This BAX antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the BAX antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    BAX (BCL2-Associated X Protein (BAX))

    Alternative Name

    BAX

    Background

    Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    UniProt

    Q07812

    Pathways

    p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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