CDK2 antibody (AA 1-30)

Catalog No. ABIN3030606

The Rabbit Polyclonal anti-CDK2 antibody (ABIN3030606) specifically detects CDK2 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for CDK2 antibody (AA 1-30) (ABIN3030606)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CDK2 Antibody

Binding Specificity: AA 1-30

Purpose: CDK2 Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Hamster, Xenopus

Purification: Antigen affinity

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this CDK2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CDK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CDK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA