CDK9 antibody (AA 251-278)
Quick Overview for CDK9 antibody (AA 251-278) (ABIN3030623)
Target
See all CDK9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 251-278
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Purpose
- Cdk9 Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Bovine
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 251-278 from the mouse protein was used as the immunogen for this Cdk9 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Cdk9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Cdk9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
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Alternative Name
- Cdk9
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Background
- Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity).
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UniProt
- Q99J95
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Pathways
- Cell Division Cycle
Target
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