S1PR5 antibody (AA 219-247)

Catalog No. ABIN3032714

The Rabbit Polyclonal anti-S1PR5 antibody is suitable to detect S1PR5 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for S1PR5 antibody (AA 219-247) (ABIN3032714)

Target: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-S1PR5 Antibody

Binding Specificity: AA 219-247

Purpose: EDG8 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 219-247 from the human protein was used as the immunogen for this EDG8 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the EDG8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EDG8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for S1PR5

Target: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Alternative Name: EDG8

Background: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1, MIM 601974) are S1P receptors, others (e.g., EDG2, MIM 602282) are LPA receptors.

UniProt: Q9H228