MAPK10 antibody (AA 1-30)

Catalog No. ABIN3031827

Product Details anti-MAPK10 Antibody

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Binding Specificity: AA 1-30

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this JNK3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the JNK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the JNK3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MAPK10

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Alternative Name: JNK3 (MAPK10 Products)

Synonyms: MAPK10 antibody, zgc:123234 antibody, DKFZp459H0638 antibody, Jnk3 antibody, SAPKC antibody, SAPb antibody, Serk2 antibody, JNK3 antibody, JNK3A antibody, PRKM10 antibody, SAPK1b antibody, p493F12 antibody, p54bSAPK antibody, C230008H04Rik antibody, JNK3B1 antibody, JNK3B2 antibody, SAPK(beta) antibody, ATMPK10 antibody, MAP kinase 10 antibody, mitogen-activated protein kinase 8 S homeolog antibody, mitogen-activated protein kinase 10 antibody, mitogen activated protein kinase 10 antibody, MAP kinase 10 antibody, mapk8.S antibody, MAPK10 antibody, mapk10 antibody, Mapk10 antibody, MPK10 antibody

Background: JNK3 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.

UniProt: P53779

Pathways: MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades