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MCL-1 antibody (AA 217-245)

MCL1 Reactivity: Human IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031297
$578.58
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  • Target See all MCL-1 (MCL1) Antibodies
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    Binding Specificity
    • 24
    • 23
    • 15
    • 14
    • 12
    • 12
    • 11
    • 11
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-245
    Reactivity
    • 170
    • 85
    • 72
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 156
    • 13
    • 8
    • 1
    Rabbit
    Clonality
    • 158
    • 22
    Polyclonal
    Conjugate
    • 85
    • 14
    • 13
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MCL-1 antibody is un-conjugated
    Application
    • 120
    • 81
    • 63
    • 47
    • 27
    • 26
    • 25
    • 24
    • 12
    • 9
    • 7
    • 6
    • 4
    • 2
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Rat
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 217-245 from the human protein was used as the immunogen for this MCL1 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the MCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    Alternative Name
    MCL1 (MCL1 Products)
    Synonyms
    BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, SNORA63 antibody
    Background
    This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
    UniProt
    Q07820
    Pathways
    MAPK Signaling
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