OGT antibody (AA 1017-1046)

Catalog No. ABIN3032083

This Rabbit Polyclonal antibody specifically detects OGT in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for OGT antibody (AA 1017-1046) (ABIN3032083)

Target: OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-OGT Antibody

Binding Specificity: AA 1017-1046

Purpose: OGT Antibody

Cross-Reactivity (Details): Expected species reactivity: Rat, Pig, Rabbit

Purification: Purified

Immunogen: A portion of amino acids 1017-1046 from the human protein was used as the immunogen for this OGT antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the OGT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the OGT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for OGT

Target: OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT))

Alternative Name: OGT

Background: O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal.

UniProt: O15294

Pathways: Regulation of Carbohydrate Metabolic Process