Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PDGFRA antibody (AA 740-769)

PDGFRA Reactivity: Human IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032251
$578.58
Plus shipping costs $45.00
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all PDGFRA Antibodies
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Binding Specificity
    • 23
    • 18
    • 17
    • 16
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 740-769
    Reactivity
    • 274
    • 144
    • 86
    • 20
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 255
    • 36
    • 4
    • 1
    Rabbit
    Clonality
    • 249
    • 47
    Polyclonal
    Conjugate
    • 118
    • 22
    • 20
    • 19
    • 15
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    This PDGFRA antibody is un-conjugated
    Application
    • 161
    • 123
    • 80
    • 66
    • 54
    • 54
    • 38
    • 25
    • 23
    • 14
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Rat, Xenopus
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 740-769 from the human protein was used as the immunogen for this PDGFR alpha antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the PDGFR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the PDGFR alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    Alternative Name
    PDGFR alpha (PDGFRA Products)
    Synonyms
    AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
    Background
    PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
    UniProt
    P16234
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
You are here:
Support