ATF2 antibody (pSer322)
Quick Overview for ATF2 antibody (pSer322) (ABIN3029846)
Target
See all ATF2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer322
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Purpose
- Phospho-ATF2 Antibody (pS322)
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Purification
- Antigen affinity
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Immunogen
- This phospho-ATF2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS322 of human ATF2.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the phospho-ATF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the phospho-ATF2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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Alternative Name
- ATF2
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Background
- ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
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UniProt
- P15336
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Pathways
- MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Target
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