DNMT1 antibody (pSer1105)
Quick Overview for DNMT1 antibody (pSer1105) (ABIN3030756)
Target
See all DNMT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer1105
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Purpose
- Phospho-Dnmt1 Antibody (pS1105)
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Antigen affinity
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Immunogen
- This phospho-Dnmt1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1105 of human Dnmt1.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the phospho-Dnmt1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the phospho-Dnmt1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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Alternative Name
- Dnmt1
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Background
- DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [Wiki]
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UniProt
- P26358
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Pathways
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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