PINK1 antibody (AA 237-266)
Quick Overview for PINK1 antibody (AA 237-266) (ABIN3028955)
Target
See all PINK1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 237-266
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Purpose
- PINK Antibody
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Purification
- Purified
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Immunogen
- A portion of amino acids 237-266 from human PINK1 was used as the immunogen for this PINK antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the PINK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the PINK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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Alternative Name
- PINK
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Background
- Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
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UniProt
- Q9BXM7
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Pathways
- Autophagy
Target
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