PRDM16 antibody (AA 771-804)

Catalog No. ABIN3032299

This Rabbit Polyclonal antibody specifically detects PRDM16 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for PRDM16 antibody (AA 771-804) (ABIN3032299)

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRDM16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRDM16 Antibody

Binding Specificity: AA 771-804

Purpose: PRDM16 Antibody

Purification: Antigen affinity

Immunogen: This PRDM16 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 771-804 amino acids from the Central region of human PRDM16.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PRDM16 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PRDM16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRDM16

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Alternative Name: PRDM16

Background: Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

UniProt: Q9HAZ2

Pathways: Stem Cell Maintenance, Brown Fat Cell Differentiation