Progesterone Receptor antibody (Isoform A)

Catalog No. ABIN3032307

The Rabbit Polyclonal anti-Progesterone Receptor antibody (ABIN3032307) specifically detects Progesterone Receptor in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Progesterone Receptor antibody (Isoform A) (ABIN3032307)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 523-550, Isoform A

Purpose: Progesterone Receptor Antibody / Isoform A & B

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity

Immunogen: A portion of amino acids 523-550 from the human protein was used as the immunogen for this Progesterone Receptor antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Progesterone Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: Progesterone Receptor

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration