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Retinoblastoma Protein (Rb) antibody (AA 858-886)

Name: Retinoblastoma Protein (Rb) antibody (AA 858-886)
SKU: ABIN3029813
Price: 649.42 USD
Availability: InStock

The Rabbit Polyclonal anti-Retinoblastoma Protein (Rb) antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect Retinoblastoma Protein (Rb) in samples from Human.

IHC analysis of FFPE human testis tissue stained with Retinoblastoma antibody (Retinoblastoma Protein (Rb) antibody (AA 858-886))

IHC

Western blot analysis of Retinoblastoma antibody and 293 lysate (Retinoblastoma Protein (Rb) antibody (AA 858-886))

Retinoblastoma antibody flow cytometric analysis of 293 cells (green) compared to a negative control (blue). (Retinoblastoma Protein (Rb) antibody (AA 858-886))

FACS

5 images

Catalog No. ABIN3029813

Quick Overview for Retinoblastoma Protein (Rb) antibody (AA 858-886) (ABIN3029813)

Target

See all Retinoblastoma Protein (Rb) (Rb Protein) Antibodies

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivity

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

This Retinoblastoma Protein (Rb) antibody is un-conjugated

Application

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Binding Specificity
16

13

10

9

9

8

8

7

7

7

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 858-886

Cross-Reactivity (Details)

Expected species reactivity: Rat

Purification

Purified

Immunogen

A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.

Isotype

Ig Fraction
anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein Reactivity: Human ELISA, IHC, IF, DB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibody
Rb Protein Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibody
Rb Protein Reactivity: Human, Mouse WB, IHC Host: Mouse Monoclonal 172C1094 unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibody
Rb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibody
Rb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibody
Rb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) antibody
Rb Protein Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 7E4B8 unconjugated

anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibody
Rb Protein Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Pig, Bat, Horse WB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibody
Rb Protein Reactivity: Human, Cow, Dog, Pig, Bat, Guinea Pig WB Host: Rabbit Polyclonal unconjugated

anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibody
Rb Protein Reactivity: Human, Mouse, Monkey WB Host: Rabbit Polyclonal unconjugated

Application Notes

Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions

For Research Use only
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Aliquot the Retinoblastoma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Alternative Name

Retinoblastoma

Background

RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.

UniProt

P06400

Pathways

Mitotic G1-G1/S Phases