SMAD6 antibody (AA 357-386)

Catalog No. ABIN3032628

This anti-SMAD6 antibody is a Rabbit Polyclonal antibody detecting SMAD6 in WB and ELISA. Suitable for Mouse.

Quick Overview for SMAD6 antibody (AA 357-386) (ABIN3032628)

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMAD6 Antibody

Binding Specificity: AA 357-386

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 357-386 from the human protein was used as the immunogen for this SMAD6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SMAD6

Target: SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))

Alternative Name: SMAD6

Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: O43541

Pathways: Chromatin Binding