TLE2 antibody (AA 637-665)

Catalog No. ABIN3029207

Product Details anti-TLE2 Antibody

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Binding Specificity: AA 637-665

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 637-665 from the human protein was used as the immunogen for this TLE2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TLE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TLE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TLE2

Target: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Alternative Name: TLE2 (TLE2 Products)

Synonyms: TLE2 antibody, ESG antibody, ESG2 antibody, GRG2 antibody, Grg2 antibody, mKIAA4188 antibody, transducin like enhancer of split 2 antibody, transducin-like enhancer of split 2 antibody, TLE2 antibody, Tle2 antibody

Background: TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

UniProt: Q04725

Pathways: WNT Signaling