TLR4 antibody (AA 669-698)
-
- Target See all TLR4 Antibodies
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
Binding Specificity
- AA 669-698
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TLR4 antibody is un-conjugated
-
Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA
- Cross-Reactivity (Details)
- Expected species reactivity: Bovine, Pig, Hamster
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 669-698 from the human protein was used as the immunogen for this TLR4 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TLR4 Primary Antibody
-
-
- Application Notes
- Titration of the TLR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the TLR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- TLR4 (Toll-Like Receptor 4 (TLR4))
- Alternative Name
- TLR4 (TLR4 Products)
- Synonyms
- ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
- Background
- TLR4 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
- UniProt
- O00206
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
-