TLR8 antibody (AA 957-987)

Catalog No. ABIN3029181

This anti-TLR8 antibody is a Rabbit Polyclonal antibody detecting TLR8 in WB, IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for TLR8 antibody (AA 957-987) (ABIN3029181)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TLR8 Antibody

Binding Specificity: AA 957-987

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 957-987 from the mouse protein was used as the immunogen for this TLR8 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TLR8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TLR8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Alternative Name: TLR8

Background: TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

UniProt: P58682

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades