TRF1 antibody (AA 337-366)

Catalog No. ABIN3029109

Product Details anti-TRF1 Antibody

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Binding Specificity: AA 337-366

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Hamster

Purification: Purified

Immunogen: A portion of amino acids 337-366 from the human protein was used as the immunogen for this TRF1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: TRF1 (TERF1 Products)

Synonyms: PIN2 antibody, TRBF1 antibody, TRF antibody, TRF1 antibody, hTRF1-AS antibody, t-TRF1 antibody, wu:fb74c04 antibody, TERF1 antibody, DKFZp459A0713 antibody, Pin2 antibody, Trbf1 antibody, Trf1 antibody, terf1 antibody, trf1 antibody, telomeric repeat binding factor 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 antibody, telomeric repeat binding factor (NIMA-interacting) 1 L homeolog antibody, TERF1 antibody, Terf1 antibody, terf1 antibody, Trf1 antibody, terf1.L antibody

Background: TERF1/TRF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity