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Tuberin antibody (AA 479-508)

The Rabbit Polyclonal anti-Tuberin antibody has been validated for ELISA and WB. It is suitable to detect Tuberin in samples from Human.
Catalog No. ABIN3029312

Quick Overview for Tuberin antibody (AA 479-508) (ABIN3029312)

Target

See all Tuberin (TSC2) Antibodies
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity

  • 273
  • 180
  • 118
  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Tuberin antibody is un-conjugated

Application

  • 200
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  • 62
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  • 33
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  • 14
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ELISA, Western Blotting (WB)
  • Binding Specificity

    • 35
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    • 11
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    • 1
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    • 1
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    AA 479-508

    Cross-Reactivity (Details)

    Expected species reactivity: Mouse, Rat

    Purification

    Antigen affinity purified

    Immunogen

    A portion of amino acids 479-508 from the human protein was used as the immunogen for this TSC2 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    Alternative Name

    TSC2

    Background

    Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

    UniProt

    P49815

    Pathways

    RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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