JUP antibody (N-Term)

Catalog No. ABIN4956513

The Guinea Pig Polyclonal anti-JUP antibody (ABIN4956513) specifically detects JUP in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for JUP antibody (N-Term) (ABIN4956513)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-JUP Antibody

Binding Specificity: AA 5-21, N-Term

Cross-Reactivity: Human, Mouse (Murine)

Immunogen: synthetic N-terminus of human plakoglobin (aa 5-21)

Application Details

Application Notes: Dilution for IHC: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: serum

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: plakoglobin

Background: Specific detection of Mr 83 000 Plakoglobin, "band 5" polypeptide of intercellular adhering junctions (also described as γ-catenin). Excellent marker for all forms of intercellular adhering junctions, such as: desmosomes of epithelial and myocardial cells (incl. cultured cells), zonulae and fasciae adherentes of epithelia, endothelia of blood vessels and myocardial cells, adherens-type junctions (e.g. lens tissue, pigmented retinal cells, Sertoli cells of testis). Especially useful for studying plakoglobin mutations in cardiomyopathies (e.g. ARVC)

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location