H2AFX antibody (Ser139)
Quick Overview for H2AFX antibody (Ser139) (ABIN4966187)
Target
See all H2AFX AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- Ser139
-
Purpose
- Anti-H2A,XS139p | H2A,X phosphorylated serine 139
-
Cross-Reactivity (Details)
-
Human
Not reactive in: plants -
Purification
- Immunogen affinity purified serum
-
Immunogen
- KLH-conjugated synthetic peptide
-
-
-
-
Application Notes
- 1: 10 000 (Dot), 1: 10 000 (ELISA), 1: 1000 (WB)
-
Comment
-
Antibody is present in PBS with 0.05 % sodium azide and 0.05% ProClin 300.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Immunogen affinity purified serum in PBS. Contains 0.05 % sodium azide.
-
Preservative
- ProClin, Sodium azide
-
Precaution of Use
- This product contains Sodium azide, ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
-
Storage
- -20 °C
-
Storage Comment
- Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
-
-
- H2AFX (H2A Histone Family, Member X (H2AFX))
-
Alternative Name
- H2A.X (H2A.XS139p)
-
Background
-
Background: Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. H2A.XS139p appears during apoptosis and is probably involved in DNA repair.
Additional information: Antibody is provided in PBS containing 0,05 % azide and 0,05 % ProClin 300
-
Molecular Weight
- 15 kDa
-
Gene ID
- 3014
-
UniProt
- P16104
-
Pathways
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
Target
-