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H2AFX antibody (Ser139)

The Rabbit Polyclonal anti-H2AFX antibody is suitable to detect H2AFX in samples from Human. It has been validated for WB, ELISA, IF and DB.
Catalog No. ABIN4966187
$803.21
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 6 to 10 Business Days

Quick Overview for H2AFX antibody (Ser139) (ABIN4966187)

Target

See all H2AFX Antibodies
H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity

  • 203
  • 104
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  • 19
  • 15
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Human

Host

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  • 23
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Rabbit

Clonality

  • 120
  • 87
Polyclonal

Conjugate

  • 122
  • 10
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This H2AFX antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Dot Blot (DB)
  • Binding Specificity

    • 42
    • 21
    • 18
    • 9
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    • 5
    • 5
    • 4
    • 3
    • 3
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    Ser139

    Purpose

    Anti-H2A,XS139p | H2A,X phosphorylated serine 139

    Cross-Reactivity (Details)

    Human
    Not reactive in: plants

    Purification

    Immunogen affinity purified serum

    Immunogen

    KLH-conjugated synthetic peptide
  • Application Notes

    1: 10 000 (Dot), 1: 10 000 (ELISA), 1: 1000 (WB)

    Comment

    Antibody is present in PBS with 0.05 % sodium azide and 0.05% ProClin 300.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Immunogen affinity purified serum in PBS. Contains 0.05 % sodium azide.

    Preservative

    ProClin, Sodium azide

    Precaution of Use

    This product contains Sodium azide, ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

    Storage

    -20 °C

    Storage Comment

    Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
  • Target

    H2AFX (H2A Histone Family, Member X (H2AFX))

    Alternative Name

    H2A.X (H2A.XS139p)

    Background

    Background: Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. H2A.XS139p appears during apoptosis and is probably involved in DNA repair.

    Additional information: Antibody is provided in PBS containing 0,05 % azide and 0,05 % ProClin 300

    Molecular Weight

    15 kDa

    Gene ID

    3014

    UniProt

    P16104

    Pathways

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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