H2AFX antibody (Ser139)

Catalog No. ABIN4966187

The Rabbit Polyclonal anti-H2AFX antibody has been validated for WB, ELISA, IF and DB. It is suitable to detect H2AFX in samples from Human.

Quick Overview for H2AFX antibody (Ser139) (ABIN4966187)

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Dot Blot (DB)

Product Details anti-H2AFX Antibody

Binding Specificity: Ser139

Cross-Reactivity (Details): Not reactive in: No confirmed exceptions from predicted reactivity known at the moment

Immunogen: KLH-conjugated synthetic peptide

Application Details

Application Notes: 1: 10 000 (Dot), 1: 10 000 (ELISA), 1: 1000 (WB)

Comment:

Antibody is present in PBS with 0.05 % sodium azide and 0.05% ProClin 300.

Restrictions: For Research Use only

Handling

Storage Comment: Store at -20°C, make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tubes.

Target Details for H2AFX

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name: H2A.X (H2A.XS139p)

Background: Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. H2A.XS139p appears during apoptosis and is probably involved in DNA repair.

Molecular Weight: 15 kDa

UniProt: P16104

Pathways: Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus