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HK3 antibody
HK3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HK3 Antibody
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Target
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HK3
(Hexokinase 3 (White Cell) (HK3))
Reactivity
All reactivities for HK3 antibodies
Human
Host
All hosts for HK3 antibodies
Rabbit
Clonality
All clonalities for HK3 antibodies
Polyclonal
Conjugate
All conjugates for HK3 antibodies
This HK3 antibody is un-conjugated
Application
All applications for HK3 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of HXK III protein. (region surrounding Val848)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % by SDS-PAGE
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Application Details
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Application Notes
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HK3
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Target
HK3
(Hexokinase 3 (White Cell) (HK3))
Alternative Name
Hexokinase-3 (HK3 Products )
Synonyms
HKIII antibody, HXK3 antibody, APS antibody, KLK2A1 antibody, PSA antibody, hK3 antibody, HK III antibody, HK-III antibody, T2E6.5 antibody, T2E6_5 antibody, hexokinase 3 antibody, RNU73859 antibody, hexokinase 3 antibody, kallikrein related peptidase 3 antibody, HK3 antibody, KLK3 antibody, Hk3 antibody, HXK3 antibody
Background
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.Synonyms: HK3, HKIII, Hexokinase type III
Molecular Weight
approx. 99 kDa
Gene ID
3101
NCBI Accession
NP_002106
UniProt
P52790
Pathways
Carbohydrate Homeostasis , Warburg Effect
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