CDX4 antibody (AA 185-284) (Alexa Fluor 680)

Catalog No. ABIN4999849

Product Details anti-CDX4 Antibody (Alexa Fluor 680)

Target: CDX4 (Caudal Type Homeobox 4 (CDX4))

Binding Specificity: AA 185-284

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDX4 antibody is conjugated to Alexa Fluor 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDX4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDX4

Target: CDX4 (Caudal Type Homeobox 4 (CDX4))

Alternative Name: CDX4 (CDX4 Products)

Synonyms: Xcad3 antibody, Xcad-3 antibody, Xtcad3 antibody, MGC68909 antibody, MGC130769 antibody, CDXB antibody, CDX4 antibody, CHUNP6923 antibody, cad1 antibody, cb546 antibody, cdx1 antibody, id:ibd1215 antibody, id:ibd2812 antibody, id:ibd5107 antibody, kgg antibody, kugelig antibody, Cdx-3 antibody, Cdx-4 antibody, Cdx3 antibody, RGD1561529 antibody, cad3 antibody, cdx4 antibody, caudal type homeobox 4 antibody, caudal type homeo box 4 antibody, caudal type homeobox 4 L homeolog antibody, CDX4 antibody, cdx4 antibody, Cdx4 antibody, cdx4.L antibody

Background:

Synonyms: Caudal-type homeobox protein 4, CDX4, CDX4_HUMAN, Homeobox protein CDX-4.

Background: Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila caudal? gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord.

Gene ID: 1046