Homeobox C5 antibody (AA 151-222) (Alexa Fluor 750)

Catalog No. ABIN5004823

Product Details anti-Homeobox C5 Antibody (Alexa Fluor 750)

Target: Homeobox C5 (HOXC5)

Binding Specificity: AA 151-222

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Homeobox C5 antibody is conjugated to Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXC5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Homeobox C5

Target: Homeobox C5 (HOXC5)

Alternative Name: HOXC5 (HOXC5 Products)

Synonyms: ZF-25 antibody, hox-3.4 antibody, hoxc5 antibody, z-142 antibody, XlHbox5 antibody, hoxc5-A antibody, CP11 antibody, HOX3 antibody, HOX3D antibody, AI181837 antibody, Hox-3.4 antibody, Hox-6.2 antibody, homeobox C5 antibody, homeo box C5 antibody, homeobox C5a antibody, homeobox C5 L homeolog antibody, translation initiation factor IF-2 antibody, HOXC5 antibody, Hoxc5 antibody, hoxc5a antibody, hoxc5.L antibody, LOC607625 antibody

Background:

Synonyms: CP11, homeo box C5, homeobox C5, Homeobox protein CP11, homeobox protein Hox C5, Homeobox protein Hox-3D, Homeobox protein Hox-C5, Hox 3D, HOX3, HOX3D, HOXC5, HXC5_HUMAN, OTTHUMP00000217386.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.