RCBTB1 antibody (Alexa Fluor 680)

Catalog No. ABIN5009672

Product Details anti-RCBTB1 Antibody (Alexa Fluor 680)

Target: RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCBTB1 antibody is conjugated to Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RCBTB1/CLLD7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RCBTB1

Target: RCBTB1 (Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1))

Alternative Name: RCBTB1 (RCBTB1 Products)

Synonyms: fj43a07 antibody, zgc:56037 antibody, wu:fj43a07 antibody, MGC81035 antibody, rcbtb1 antibody, CLLD7 antibody, CLLL7 antibody, GLP antibody, RP11-185C18.1 antibody, 5430409I18Rik antibody, AW111883 antibody, RCC1 and BTB domain containing protein 1 antibody, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 antibody, regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 S homeolog antibody, RCC1 and BTB domain-containing protein 1 antibody, Rcbtb1 antibody, RCBTB1 antibody, rcbtb1 antibody, rcbtb1.S antibody, LOC100470400 antibody

Background:

Synonyms: Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, CLLD7, CLLL7 protein, Guanine nucleotide exchange factor, broad-complex, tramtrack and bric a brac, Hypothetical protein FLJ39335, RCBT1_HUMAN, Rcbtb1, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1.

Background: The BTB domain, also known as the POZ (poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. RCBTB1 (regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1), also known as GLP, CLLD7, CLLL7 or E4.5, is a 531 amino acid protein that localizes to the nucleus and contains two BTB (POZ) domains and six RCC1 repeats. Expressed ubiquitously, RCBTB1 is thought to be involved in cell cycle regulation, specifically via chromatin remodeling. The gene encoding RCBTB1 maps to a region on human chromosome 13 that is frequently deleted in B-cell chronic lymphocytic leukemia, suggesting a possible role for RCBTB1 in tumor suppression.

Gene ID: 55213