ZBED3 antibody (C-Term)

Catalog No. ABIN501141

Product Details anti-ZBED3 Antibody

Target: ZBED3 (Zinc Finger, BED-Type Containing 3 (ZBED3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBED3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Specificity: This antibody detects ED3 at C-term. The antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogen: ZBED3 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for ZBED3

Target: ZBED3 (Zinc Finger, BED-Type Containing 3 (ZBED3))

Alternative Name: ZBED3 (ZBED3 Products)

Synonyms: 0610037K01Rik antibody, 2610005H11Rik antibody, AU018975 antibody, AU024588 antibody, zinc finger BED-type containing 3 antibody, zinc finger, BED type containing 3 antibody, zinc finger, BED-type containing 3 antibody, ZBED3 antibody, Zbed3 antibody

Target Type: Viral Protein

Background: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE.Synonyms: Zinc finger BED domain-containing protein 3

Gene ID: 84327

NCBI Accession: NP_115743