FBXW7 antibody (AA 312-545)

Catalog No. ABIN5013523

This anti-FBXW7 antibody is a Rabbit Polyclonal antibody detecting FBXW7 in WB, IHC, IP and ICC. Suitable for Mouse.

Quick Overview for FBXW7 antibody (AA 312-545) (ABIN5013523)

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXW7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-FBXW7 Antibody

Binding Specificity: AA 312-545

Purpose: Polyclonal Antibody to F-Box And WD Repeat Domain Containing Protein 7 (FBXW7)

Specificity: The antibody is a rabbit polyclonal antibody raised against FBXW7. It has been selected for its ability to recognize FBXW7 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: FBXW7 (Cys312-His545)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.2-2 μg/mL,1:250-2500 Immunohistochemistry: 5-20 μg/mL,1:25-100 Immunocytochemistry: 5-20 μg/mL,1:25-100 Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Target Details for FBXW7

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Alternative Name: FBXW7

Background: AGO, CDC4, FBW7, FBX30, FBXW6, SEL-10, SEL10, Archipelago Homolog, F-box and WD-40 domain-containing protein 7

Pathways: Notch Signaling, EGFR Signaling Pathway