MAPKAP1 antibody (AA 250-522)
-
- Target See all MAPKAP1 Antibodies
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
-
Binding Specificity
- AA 250-522
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This MAPKAP1 antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Protein A Chromatography
- Immunogen
- A partial length recombinant Mip1 protein (amino acids 250-522) was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MAPKAP1 Primary Antibody
-
-
- Application Notes
- WB: 1-3 μg/mL
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
- Target
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
- Alternative Name
- SAPK interacting proten 1/Mip1 (MAPKAP1 Products)
- Synonyms
- CG10105 antibody, Dmel\\CG10105 antibody, dSin1 antibody, sin1 antibody, MAPKAP1 antibody, im:7143088 antibody, si:ch73-242f23.1 antibody, mip1 antibody, sin1b antibody, sin1g antibody, MGC53034 antibody, JC310 antibody, MIP1 antibody, SIN1 antibody, SIN1b antibody, SIN1g antibody, AI591529 antibody, D230039K05Rik antibody, Sin1 antibody, SAPK-interacting protein 1 antibody, mitogen-activated protein kinase associated protein 1 antibody, mitogen-activated protein kinase associated protein 1 L homeolog antibody, Sin1 antibody, MAPKAP1 antibody, mapkap1 antibody, Mapkap1 antibody, mapkap1.L antibody
- Background
- Stress-activated map kinase (SAPK )-interacting protein 1, also called as Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1), belongs to Stress-activated map kinase interacting protein 1 (SIN1) family. It is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors and also plays a critical role in AKT1 'Ser-473'phosphorylation. Except isoform 4 from its 6 isoforms , all can be incorporated into the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. It is ubiquitously expressed in heart and skeletal muscle. Diseases associated with MAPKAP1 include bronchiolitis obliterans organizing pneumonia and nephrogenic systemic fibrosis.
- Molecular Weight
- 50 kDa
- Gene ID
- 79109
- UniProt
- Q9BPZ7
- Pathways
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
-