RAGE antibody (AA 1-280)

Catalog No. ABIN5027503

The Rabbit Polyclonal anti-RAGE antibody is suitable to detect RAGE in samples from Human. It has been validated for WB.

Quick Overview for RAGE antibody (AA 1-280) (ABIN5027503)

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAGE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAGE Antibody

Binding Specificity: AA 1-280

Purification: Protein A Chromatography

Immunogen: A partial length recombinant RAGE protein (amino acids 1-280) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Alternative Name: RAGE

Background: RAGE (Advanced glycosylation end product-specific receptor) is a member of immunoglobulin superfamily with multiple isoforms being located on the membrane of endothelial cells. RAGE acts transporter of amyloid beta peptide across the blood brain barrier. It has also been reported that RAGE is overexpressed in Alzheimer disease. RAGE is also involved in vascular inflammation in atherosclerosis, type 2 diabetes mellitus. High levels of RAGE protein is found in brain tissue.

Molecular Weight: 42 kDa

Gene ID: 177

UniProt: Q15109

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins