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RAGE antibody (AA 1-280)
AGER
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RAGE Antibody
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Target
See all RAGE (AGER) Antibodies
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))
Binding Specificity
All epitopes for RAGE antibodies
AA 1-280
Reactivity
All reactivities for RAGE antibodies
Human
Host
All hosts for RAGE antibodies
Rabbit
Clonality
All clonalities for RAGE antibodies
Polyclonal
Conjugate
All conjugates for RAGE antibodies
This RAGE antibody is un-conjugated
Application
All applications for RAGE antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant RAGE protein (amino acids 1-280) was used as the immunogen for this antibody.
Isotype
IgG
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Application Details
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Application Notes
WB: 1-2 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for RAGE
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Target
RAGE (AGER)
(Advanced Glycosylation End Product-Specific Receptor (AGER))
Alternative Name
RAGE (AGER Products )
Synonyms
RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody
Background
RAGE (Advanced glycosylation end product-specific receptor) is a member of immunoglobulin superfamily with multiple isoforms being located on the membrane of endothelial cells. RAGE acts transporter of amyloid beta peptide across the blood brain barrier. It has also been reported that RAGE is overexpressed in Alzheimer disease. RAGE is also involved in vascular inflammation in atherosclerosis, type 2 diabetes mellitus. High levels of RAGE protein is found in brain tissue.
Molecular Weight
42 kDa
Gene ID
177
UniProt
Q15109
Pathways
Carbohydrate Homeostasis , Toll-Like Receptors Cascades , Smooth Muscle Cell Migration , S100 Proteins
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