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EGFR antibody (AA 1-405)

This Mouse Polyclonal antibody specifically detects EGFR in WB, IF and PLA. It exhibits reactivity toward Human.It has been mentioned in 1 publication
Catalog No. ABIN515185
$489.14
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 11 to 14 Business Days

Quick Overview for EGFR antibody (AA 1-405) (ABIN515185)

Target

See all EGFR Antibodies
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivity

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Human

Host

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Mouse

Clonality

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Polyclonal

Conjugate

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This EGFR antibody is un-conjugated

Application

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Western Blotting (WB), Immunofluorescence (IF), Proximity Ligation Assay (PLA)
  • Binding Specificity

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    AA 1-405

    Purpose

    Mouse polyclonal antibody raised against a full-length human EGFR protein.

    Sequence

    MRPSGTAGAA LLALLAALCP ASRALEEKKV CQGTSNKLTQ LGTFEDHFLS LQRMFNNCEV VLGNLEITYV QRNYDLSFLK TIQEVAGYVL IALNTVERIP LENLQIIRGN MYYENSYALA VLSNYDANKT GLKELPMRNL QEILHGAVRF SNNPALCNVE SIQWRDIVSS DFLSNMSMDF QNHLGSCQKC DPSCPNGSCW GAGEENCQKL TKIICAQQCS GRCRGKSPSD CCHNQCAAGC TGPRESDCLV CRKFRDEATC KDTCPPLMLY NPTTYQMDVN PEGKYSFGAT CVKKCPRNYV VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS INATNIKHFK NCTSISGDLH ILPVAFRGDS FTHTPPLDPQ ELDILKTVKE ITGLS

    Cross-Reactivity

    Human

    Characteristics

    Antibody reactive against mammalian transfected lysate.

    Immunogen

    EGFR (NP_958440.1, 1 a.a. ~ 405 a.a) full-length human protein.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Li, Fang, Wang, Tzeng, Tai, Wei, Li, Lee, Wang, Yu, Shiue, Chu, Wang, Chen, Huang: "EGFR nuclear import in gallbladder carcinoma: nuclear phosphorylated EGFR upregulates iNOS expression and confers independent prognostic impact." in: Annals of surgical oncology, Vol. 19, Issue 2, pp. 443-54, (2012) (PubMed).

  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Alternative Name

    EGFR

    Background

    Full Gene Name: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
    Synonyms: ERBB,ERBB1,HER1,PIG61,mENA

    Gene ID

    1956

    NCBI Accession

    NM_201283

    Pathways

    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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